Brain Science:
Parkinson Disease is the second most common brain disorder. It affects more than 10 million people worldwide. The breakdown of a dopamine neurons in the brain region involved in movement causes Parkinson's disease symptoms, including tremors, impaired movement and stiffness, and disrupted balance. You may recall that dopamines act as neurotransmitters. a neurotransmitter is a chemical that facilitates the transfer of signals (information) between brain cells.The communication between cells accounts for movement, thinking and most other forms of human development.
Parkinson's emerges from the disruption of the normal flow of the brain. When this normal condition is disrupted symptoms occur. There are several therapeutics emerging to treat Parkinson's. You may recall that boxing is one. What you are doing here is, by physical activity, rebuilding your brain. Another way to do this is with drugs. Recently in both parkinson and cancer research, scientists are delving deeply into enzymes called protein kinase. Enzymes are substances produced by the body which act as catalysts to bring about a chemical reaction. They, or these types, of enzymes, play a big role in accelerating or decelerating cell growth. They also regulate motion in sense that the presence or non-presense of kinese keeps the body regulated and calm. Overreacting of kinase enzymes in the brain and elsewhere can cause cancer and reactions such as tremors. So recent drug research is all about regulating kinase by identifying protein kinase inhibitors. Scientists very recently identified a specific kinase inhibitor to treat Parkinson's. They have named it but let's not get too deep. The study and development of drugs that are essentially kinase inhibitors for specific uses have brought about remarkable successes in clinical research and cancer drug discovery. The discovery of the parkinson specific inhibitor and accelerated research associated with it may prove successful in developing a new more effective treatment through drugs.
Brain Facts:
10 million people have parkinson's.
Kinase are among the most important family of enzymes in the body, as they are essential in the functioning of our body's biological system.
Inhibitors are are micro biological substances that prevent over action of kinase by altering the biochemical activity of kinase.
Inhibitors as drugs are being used to inhibit cell growth such as in cancer.
A specific inhibitor has been discovered that inhibits the over action of the of the brain that causes symptoms of parkinson's.
So What:
It is obvious that something is happening in parkinson's disease research. What is not obvious, is what the heck is it? Hopefully this blog will help in understanding. It was very difficult to write. Reading the research from the Harvard Medical Review and then translating that to something we can understand and using other sources to connect the dots, was a challenge. Most reading is deep in medical jargon. You may think this blog was deep but, trust me, this is as simple as I could come up with. I'm no brain scientist. (That should be obvious at this point!) I hope this makes sense. It appears that there is great promise in this research. The more we know about it, as it develops, the more likely it will be used effectively. If you know someone who has some form of Parkinson you might ask them to ask their doctor about protein kinase inhibitors and what is the latest about their use.
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